北京治疗白癜风哪家医院好呢 https://jbk.39.net/yiyuanzaixian/bjzkbdfyy/EngineeredCellSheetsfortheEffectiveDeliveryofAdipose-DerivedStemCellsforTendon-to-BoneHealing
组织工程细胞片可有效递送脂肪干细胞以进行肌腱-骨的愈合
作者:MyungJinShin,InKyongShim,DongMinKim,JaeHeeChoi,YuNaLee,In-HoJeon,HyojuneKim,DongjunPark,EricaKholinne,Ha-SolYang,KyoungHwanKoh
杂志:AmJSportsMed.
DOI:10./
IF:5.81
Background
Effortsarebeingmadetotreatrotatorcufftears(RCTs)thatexhibitpoorhealingandhighretearrates.Tendon-to-bonehealingusingmesenchymalstemcellsisbeingexplored,butresearchisneededtoestablisheffectivedeliveryoptions.
人们正在努力治疗不良愈合和高复发的肩袖撕裂症(RCT)。人们正在探索使用间充质干细胞进行肌腱-骨的愈合,但是需要研究有效的递送选择。
Purpose
Toevaluatetheeffectsofanadipose-derivedstemcell(ADSC)sheetonmesenchymalstemcelldeliveryfortendon-to-bonehealingofachronicRCTinratsandtodemonstratethatADSCsheetsenhancetendon-to-bonehealing.
评估脂肪来源干细胞(ADSC)片对间充质干细胞递送的大鼠慢性RCT的肌腱-骨愈合的影响,并证明ADSC片增强肌腱-骨的愈合。
Studydesign
Controlledlaboratorystudy.
对照实验室研究
Methods
Mesenchymalstemcellswereobtainedfromratadiposetissue,andacellsheetwaspreparedusingatemperature-responsivedish.Toevaluatetheefficacyofstemcellsproducedinasheetforthelesion,theexperimentwasconductedwith3groups:repairgroup,cellsheettransplantationafterrepairgroup,andcellsheet-onlygroup.Histological,biomechanical,andmicro-